The Role of Magnetic Fields in TMS
Transcranial Magnetic Stimulation (TMS) is a non-invasive therapy that has been used for treating a variety of neuropsychiatric disorders. The technique uses magnetic fields to stimulate the nerve cells in the brain. In this blog, we will discuss the role of magnetic fields in TMS.
Magnetic Fields
During a TMS session, the TMS helmet is placed on the scalp, and the magnetic field is directed towards the brain. The magnetic field produced is of a specific frequency and strength that is known to stimulate the neurons in the brain.
TMS is a non-invasive and painless method that has been used to study brain function and as a therapeutic tool for a variety of neurological and psychiatric conditions. The use of the TMS helmet allows for precise targeting of specific areas of the brain and provides a safe and effective means of delivering the magnetic field required for TMS.
Mechanism of Action
The magnetic fields generated by TMS have a variety of effects on the brain. One of the most significant effects is that they induce an electrical current in the neurons of the brain. This electrical current causes the neurons to depolarize, which means that they become more likely to fire action potentials. The depolarization of neurons can lead to changes in the connectivity of brain circuits, which can improve the symptoms of neuropsychiatric disorders.
Another effect of TMS is that it can modulate the activity of the neurotransmitters in the brain. Neurotransmitters are the chemicals that carry signals between neurons in the brain. By modulating the activity of neurotransmitters, TMS can alter how the brain processes information.
Types of Magnetic Fields
There are two main types of magnetic fields used in TMS: repetitive TMS (rTMS) and single-pulse TMS (sTMS). In rTMS, a series of magnetic pulses are delivered at a fixed frequency over a period of time. This can cause long-lasting changes in the brain. In sTMS, a single magnetic pulse is delivered to the brain. This is used to map the brain’s activity and diagnose neuropsychiatric disorders.
Safety and Side Effects
TMS is generally considered to be safe and well-tolerated. The magnetic fields used in TMS are of similar strength to those used in magnetic resonance imaging (MRI), a commonly used diagnostic tool. However, as with any medical procedure, there can be side effects. The most common side effects of TMS are headache and scalp discomfort. These side effects are usually mild and go away shortly after the procedure.
Conclusion
The role of magnetic fields in TMS is essential to understanding how the technique works. By inducing an electrical current in the neurons of the brain and modulating the activity of neurotransmitters, TMS can lead to changes in the connectivity of brain circuits, which can improve the symptoms of neuropsychiatric disorders. In addition, TMS is generally considered safe and well-tolerated, with minimal side effects. If you want to learn more about TMS and its potential benefits, don’t hesitate to contact the Center for Integrative Psychiatry.
Next Blog
The next blog will discuss the research and evidence supporting TMS as an effective treatment for neuropsychiatric disorders. Stay tuned for more information.
Sources:
- George, M. S., Wassermann, E. M., & Williams, W. A. (1996). Call to action: Mechanisms of action of stimulation therapies. Biological Psychiatry, 40(6), 545-548.
- Barker, A. T., Jalinous, R., & Freeston, I. L. (1985). Non-invasive magnetic stimulation of human motor cortex. The Lancet, 325(8437), 1106-1107.
- Hallett, M. (2000). Transcranial magnetic stimulation and the human brain. Nature, 406(6792), 147-150.
- George, M. S., Wassermann, E. M., & Williams, W. A. (1996). Callahan A, Ketter TA, Basser P, et al. Daily repetitive transcranial magnetic stimulation (rTMS) improves mood in depression. NeuroReport, 7(14), 2527-2532.
- Rossi, S., Hallett, M., Rossini, P. M., & Pascual-Leone, A. (2009). Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clinical neurophysiology, 120(12), 2008-2039.
- Chen, R., Classen, J., Gerloff, C., Celnik, P., Wassermann, E. M., Hallett, M., … & Cohen, L. G. (1997). Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation. Neurology, 48(5), 1398-1403.
- Lefaucheur, J. P., André-Obadia, N., Antal, A., Ayache, S. S., Baeken, C., Benninger, D. H., … & Garcia-Larrea, L. (2014). Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS). Clinical neurophysiology, 125(11), 2150-2206.
- Fregni, F., Boggio, P. S., Nitsche, M., Bermpohl, F., Antal, A., Feredoes, E., … & Pascual-Leone, A. (2005). Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory. Experimental brain research, 166(1), 23-30.
