Spravato®
Spravato®
Discover the transformation you've been looking for with the most recent
FDA-approved treatment.
SPRAVATO / Esketamine is a ground-breaking treatment for major depression. This treatment is available at The Center For Integrative Psychiatry. Esketamine is a nasal spray that is prescribed to treat treatment-resistant depression. Unlike oral antidepressants, which can take weeks to months to work, the effects are typically felt within hours, opening a path to healing for patients who have not responded to oral antidepressants and/or therapy alone.
Spravato Treatment Process Steps
1. Intake & Preparation
Insurance coverage usually pays for Spravato treatment, but they have some requirements that we at The Center For Integrative Psychiatry will help you navigate. Most companies require that you have not had success with a couple of antidepressant medications, and they will require a prior authorization. Our staff will assist every step of the way!
2. In-Person Initial Evaluation
Here is what you can expect. This is where you get to come into tour Center for Integrative Psychiatry and you will meet our friendly staff. You and your provider will review your diagnosis and medication history as well as your further treatment options, which could include Spravato. We do NOT provide the first treatment during this initial evaluation.
3. Getting Ready!
Spravato, is self-administered under our direct supervision and sprayed into the nostrils. We will check your vital signs periodically for two hours at least in or comfortable facility. Please note that at the Center for Integrative Psychiatry, to maintain your safety, cell phones use, except for music, is disallowed during treatment sessions (we will explain why during the initial visit) and you will need to have a designated driver after each treatment session.
Steps for therapy
1. Prior Authorization and Meeting Criteria
2. In-Person Initial Evaluation
3. Get Ready for Spravato!
1
Insurance coverage usually pays for Spravato treatment, but they have some requirements that we will help you navigate. Most companies require that you have not had success with a couple of antidepressant medications, and they will require a prior authorization. Our staff will assist every step of the way!
2
This is where you get to come into tour CIP and you will meet our friendly staff. You and your provider will review your diagnosis and medication history as well as your further treatment options, which could include Spravato. We do NOT provide the first treatment during this initial evaluation.
3
EsKetamine, or Spravato, is self-administered under our direct supervision and sprayed into the nostrils. We will check your vital signs periodically for two hours at least in or comfortable facility. Please note that at CIP, to maintain your safety, cell phones use, except for music, is disallowed during treatment sessions (we will explain why during the initial visit) and you will need to have a designated driver after each treatment session.
The Science Behind Spravato
The exact mechanism of Spravato is unknown, however we believe that it works by blocking the NMDA receptor. This leads to a downstream increased release of Brain Derived Neurotrophic Factor (BDNF). BDNF is an amazing molecule which does a tremendous amount of good in the brain, including helping the brain to physically grow, by establishing new connections between nerve cells. This is called “neuro-genesis”, or the creation of new “neurons” or in this case new neuronal connections. Absolutely amazing!
This is where the benefits of Spravato and its derivatives seem to come from mostly. In other words, depression can cause us to lose or weaken neuronal connections, but antidepressant as well as Spravato, meditating, TMS, exercise and many many other things can help us to regrow new brain cell connections. These new connections can help us think faster, feel better and be more relaxed and in control!
To know more about Spravato please check this.
The Science behind Spravato
Spravato targets the glutamate system in the brain, which is essential for normal brain function. Glutamate is a neurotransmitter that is abundant in the body and is responsible for sending a signal between nerve cells.
Although the precise mechanism of action of Spravato is unknown, it is thought to create new brain connections, allowing behavioral and cognitive changes to occur more readily and rapidly in patients with treatment-resistant depression. In clinical trials, patients treated with Spravato had a 69% response rate and a 52% remission rate.
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